Sensing Voltage Dynamics with Differential Intensity Surface Plasmon Resonance Systems
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Revision as of 13:00, 30 April 2016 by Sidahmed
- This project was directed at researching the engineering fundamentals of label-free detection of bio-electrical signals using surface plasmon resonance (SPR). The project is based on the sensitivity of surface plasmons to the voltage at the metal-electrolyte interface. It aimed to estimate the limit of the voltage detection of SPR using theoretical and experimental approaches. Therefore, the physical properties of the interface were investigated using optics and electrochemical models. The theoretical results were then validated experimentally using a bespoke SPR system. The project also aimed to investigate the ability of the sensing technique to detect the dynamic bio-electrical signals at 1 KHz.
Voltage Sensing System
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- In order to study the voltage sensitivity of surface plasmon resonance, an SPR-basedvoltage sensing system has been designed and tested. It consists of the opticalcon�guration and the electrochemical unit. The optical con�guration is used toexcite surface plasmons at the metal-electrolyte interface while the electrochemicalunit is used to control the potential at this interface. This chapter presents thedesign of the optical system and the investigation of the sources of instability. Theintegrated system has been tested for detecting the interfacial potential using theelectrochemical system and the optical system, simultaneously.